¡Es el Astrocito, Estúpido! Es la Recanalización, para Socorrer al Astrocito y Salvar la Neurona


  • Pablo Cox Unidad de Imagenología Compleja, Hospital Carlos Van Buren, Valparaíso. Departamento de Radiología, Universidad de Valparaíso. Centro de Neurología Traslacional, Universidad de Valparaíso
  • Andrés Gallardo Unidad de Imagenología Compleja, Hospital Carlos Van Buren, Valparaíso. Unidad de TeleACV, Departamento de Salud Digital, Ministerio de Salud, Chile



Palabras clave:

Isquemia Cerebral, Trombectomía, Astrocito, Sistema Glinfático


Los últimos ensayos clínicos de pacientes con ataque cerebrovascular sometidos a trombectomía mecánica v/s mejor tratamiento médico, mostraron resultados favorables incluso en pacientes con un “core” isquémico extenso. En un metaanálisis reciente se mostró que incluso era beneficioso para pacientes con una isquemia extensa y hasta 24 hrs desde la última vez visto bien (Saraj, 2023). En este artículo revisamos distintos ensayos clínicos que evalúan la trombectomía, la fisiopatología de la isquemia y proponemos al astrocito y el sistema glinfático, como foco principal en los efectos del tratamiento. Planteamos la necesidad de cambiar el paradigma del tratamiento actual en pacientes  con “core” isquémico extenso, a su vez la necesidad de considerar estos cambios en el financiamiento y la organización de una red nacional de trombectomía por parte de las autoridades gubernamentales.


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Cómo citar

Cox, P. ., & Gallardo, A. (2024). ¡Es el Astrocito, Estúpido! Es la Recanalización, para Socorrer al Astrocito y Salvar la Neurona. Cuadernos Médico Sociales, 63(4), 29–39. https://doi.org/10.56116/cms.v63.n4.2023.1760